The Evidence for a Narrower Thyrotropin Reference Range Is Compelling

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Are serum thyrotropin levels within the reference range associated with endothelial function?

AIMS High serum thyrotropin (TSH) levels within the reference range might be associated with an increased cardiovascular risk. In the present study, we investigated the association between serum TSH levels and flow-mediated dilation (FMD) as a measure of endothelial dysfunction. METHODS AND RESULTS The study population comprised 1364 subjects (670 women) aged 25-85 years with serum TSH levels...

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Correspondence: Oscar MP Jolobe 1 Philip Godlee Lodge, 842 Wilmslow Road, Manchester M20 2DS, UK Tel +44 16 1448 9034 Email [email protected] To the editor The assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans appears to be at odds with the observation that “TSH distribution shifts towards higher concentra...

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ژورنال

عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism

سال: 2005

ISSN: 0021-972X,1945-7197

DOI: 10.1210/jc.2005-0455